Bone Morphogenetic Proteins: Systems Biology Regulators

Name: Bone Morphogenetic Proteins: Systems Biology Regulators
Brand: Springer International Publishing AG
SKU: 9783319475059
Price: 209.83 EUR
Availability: InStock

Автор: Slobodan Vukicevic, Kuber T. Sampath

Език:

Корици: С твърди корици

Издател: Springer International Publishing AG

Наличност: Външен склад

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209.83 € 410.39 лв

BMP proteins, also referred as and Growth and Differentiation Factors, are members of TGF-beta super...

Информация за книгата

Автор

Slobodan Vukicevic, Kuber T. Sampath

Език

Английски език

Корици

Книга - С твърди корици

Издадена

2017

страници

445

EAN

9783319475059

ISBN

3319475053

Enbook ID

14231491

Издател

Springer International Publishing AG

Теглоt

8933

Размери

155 x 235 x 27

Пълно описание

BMP proteins, also referred as and Growth and Differentiation Factors, are members of TGF-beta superfamily and are highly conserved from fruit fly to mammals and responsible for the formation of essentially every organ during embryo development and involved in adult tissue injury and repair. BMPs establish their extracellular gradient by interacting with their respective antagonists and regulate their function through SMAD-dependent down-stream signaling effector genes. This book focuses on the salient features of BMPs biology and the advances in their structure and function and in downstream signaling, as well as their governance in systems biology from bone and dentin to the kidney, cancer, diabetes, iron homeostasis and angiogenesis, including rare musculoskeletal disorders. The volume addresses scientists and professionals dealing with metabolic disorders, nutrition, systems biology diseases, rare musculoskeletal conditions, and disorders related to iron metabolism, including anemia of chronic disease, hereditary hemochromatosis and beta thalassemia.

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Bone Morphogenetic Proteins: Systems Biology Regulators

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