Cancer Informatics

Name: Cancer Informatics
Brand: LAP Lambert Academic Publishing
SKU: 9783659234255
Price: 70.17 EUR
Availability: InStock

Computational Analysis Of Significant Missense Mutations In Various Cancer Genes And Their Drug Targets

Автор: R. Rajasekaran, Rao Sethumadhavan, P. Chandrasekaran

Език:

Корици: С меки корици

Издател: LAP Lambert Academic Publishing

Наличност: Налично при издателя, по поръчка

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70.17 € 137.25 лв

Cancer is a complex genetic disease as a result of accumulation of mutations. The study of these mut...

Информация за книгата

Автор

R. Rajasekaran, Rao Sethumadhavan, P. Chandrasekaran

Език

Английски език

Корици

Книга - С меки корици

Издадена

2012

страници

280

EAN

9783659234255

Enbook ID

07062420

Издател

LAP Lambert Academic Publishing

Теглоt

433

Размери

150 x 220 x 17

Пълно описание

Cancer is a complex genetic disease as a result of accumulation of mutations. The study of these mutations not only reveals the molecular mechanism of tumoriogenesis but also provides insight for the development of novel therapeutics and diagnostic approaches. Missense mutations are among the most common types of mutations and can cause a various types of cancer. Deleterious effects of missense mutations are usually attributed to changes in the primary amino acid sequence, protein structure and function. Identifying the detrimental missense mutations in cancer genes and their drug targets are the challenging task in cancer biology. As missense variants are commonly identified in genomic sequence, only a small fraction directly contributed to oncogenesis. The ability to distinguish those missense changes that contribute to cancer progression and drug resistance from those that do not is a difficult problem usually accomplished through functional in vivo analysis. Hence, this book provides a computational protocol for identifying the detrimental missense mutation of various cancer genes in a lucid manner.

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Cancer Informatics

Computational Analysis Of Significant Missense Mutations In Various Cancer Genes And Their Drug Targets

Информация за книгата

Пълно описание

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