Книга Chalcone based sulfonohydrazides as possible antimicrobial agents Muhammad Athar Abbasi

Chalcone based sulfonohydrazides as possible antimicrobial agents

3,4-Dimethoxybenzaldehyde, 4,5-Dimethoxy-2-[3-oxo-3-phenylprop-1-en-1-yl]benzene Sulfonic Acid Derivatives

Език: Английски език
Корици: С меки корици
Наличност: Външен склад
Изпращаме след 5-8 дни
36.54 71.46 лв
A series of potential biologically active 4,5-dimethoxy-2-[3-oxo-3-phenylprop-1-en-1-yl]benzenesulfo...

Информация за книгата

Език
Английски език
Корици
Книга - С меки корици
Издадена
2016
страници
64
EAN
9783659874239
Enbook ID
10937736
Теглоt
112
Размери
150 x 220 x 4

Пълно описание

A series of potential biologically active 4,5-dimethoxy-2-[3-oxo-3-phenylprop-1-en-1-yl]benzenesulfonamides was synthesized. 3,4-Dimethoxybenzaldehyde was condensed with acetophenone followed by its chlorosulfonation to get 4,5-dimethoxy-2-[3-oxo-3-phenylprop-1-en-1-yl]benzenesulfonyl chloride, which was further reacted with a number of amines and hydrazides to get the 4,5-dimethoxy-2-[3-oxo-3-phenylprop-1-en-1-yl]benzenesulfonic acid derivatives. All the synthesized compounds were subjected to preliminary evaluation for their antibacterial activity against selected strains of gram positive and gram negative bacteria. Some of the assayed compounds showed marked activity.

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