Coated Implant Surfaces

Name: Coated Implant Surfaces
Brand: Sudwestdeutscher Verlag Fur Hochschulschriften AG
SKU: 9783838135106
Price: 63.96 EUR
Availability: InStock

Influence of RGD Coating in Combination with Surface Properties on the Adhesion Process of Osteoblasts

Автор: Petra M. Dorfner

Език:

Корици: С меки корици

Издател: Sudwestdeutscher Verlag Fur Hochschulschriften AG

Наличност: Външен склад

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63.96 € 125.10 лв

A profound knowledge of bony in growth is the basis for the development of biofunctionalized implant...

Информация за книгата

Автор

Petra M. Dorfner

Език

Английски език

Корици

Книга - С меки корици

Издадена

2012

страници

140

EAN

9783838135106

ISBN

3838135105

Enbook ID

06920641

Издател

Sudwestdeutscher Verlag Fur Hochschulschriften AG

Теглоt

213

Размери

152 x 229 x 8

Пълно описание

A profound knowledge of bony in growth is the basis for the development of biofunctionalized implants. The positive influence of RGD peptides and surface properties of implant material on cell adhesion is well known. With the aim to reveal potential synergies, we functionalized different Ti6Al4V disks with highly active v-specific RGD peptides. Our integrin binding studies yielded the most promising results for the combination of peptide coating and rough surfaces. Cell adhesion experiments performed with characterized human primary osteoblasts demonstrated that cells adhere more strongly on rough surfaces coated with peptide compared to smooth ones. We showed that peptide coating and surface topography influence the adhesion kinetics particularly at the early stage. Cell spreading was accelerated on Ti6Al4V disks immobilized with peptides within the first hour, while after longer incubation times this effect is less pronounced. The combination of RGD peptide coating with optimized topological surface properties of implant materials bears the potential to increase osseointegration.

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Coated Implant Surfaces

Influence of RGD Coating in Combination with Surface Properties on the Adhesion Process of Osteoblasts

Информация за книгата

Пълно описание

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