The annual conference of the European Association for Computer Science Logic (EACSL), CSL 2008, was held in Bertinoro, near Bologna (Italy), September 16 19, 2008. The conference series started as a program of International Wo- shops on Computer Science Logic, and then at its sixth meeting became the Annual Conference of the EACSL. This conference was the 22nd meeting and 17th EACSL conference; it was organized by the Department of Computer S- ence of Alma Mater Studiorum Universita` di Bologna. CSL2008wasprecededonMonday,September15thbythesymposiumBri- ing Logic and Computer Science on the occasion of the 60th birthday of Johann A. Makowsky. In response to the call for papers, a total of 102 abstracts were submitted to CSL 2008 of which 87 were followed by a full paper. The Program Committee selected 31 papers for presentation at the conference and publication in these proceedings,during a one-weekelectronicdiscussion on the EasyChairplatform; each paper was refereed by three to ?ve reviewers. The Program Committee invited lectures from Luca Cardelli, Pierre-Louis Curien, Jean-PierreJouannaud,and Wolfgang Thomas. The papers providedby the invited speakers appear at the beginning of this volume. Createdin 2005,the AckermannAwardis the EACSLOutstanding Disser- tion Awardfor Logicin Computer Science, sponsoredfor the years2007-2009by LogitechS.A. The awardrecipientfor 2008wasKrishnenduChatterjee,who was invited to present his work at the conference. Citation for the award, abstract of the thesis, and a biographical sketch of the recipient may be found at the end of the proceedings.