Cytochrome P450

Name: Cytochrome P450
Brand: Springer-Verlag New York Inc.
SKU: 9781071615447
Price: 123.74 EUR
Availability: InStock

In Vitro Methods and Protocols

Автор: Zhengyin Yan, Gary W. Caldwell

Език:

Корици: С меки корици

Издател: Springer-Verlag New York Inc.

Наличност: Външен склад

Изпращаме след 5-8 дни

123.74 € 242.01 лв

This collection explores detailed experimental protocols necessary for setting up a variety of in vi...

Информация за книгата

Автор

Zhengyin Yan, Gary W. Caldwell

Език

Английски език

Корици

Книга - С меки корици

Издадена

2022

страници

379

EAN

9781071615447

Enbook ID

39319364

Издател

Springer-Verlag New York Inc.

Теглоt

743

Размери

178 x 254 x 22

Пълно описание

This collection explores detailed experimental protocols necessary for setting up a variety of in vitro cytochrome P450 (CYP) assays that are vital in selecting drug candidates in a drug discovery pipeline. Major factors affecting drug metabolism include CYP expression levels, kinetic parameters for individual CYP enzymes, CYP inhibition and induction, time-dependent inhibition (TDI), CYP stability, non-CYP stability, UDP-glucuronosyltransferases (UGT) stability, excretion mechanisms, and drug-drug interactions (DDI), all addressed in this volume. Written for the Methods in Pharmacology and Toxicology series, chapters include helpful background information on the in vitro assay, a list of all the materials, reagents, and equipment necessary to carry out the assay, a step-by-step protocol, notes containing common and unexpected experimental problems in the assay, as well as references containing important supplementary reading. Authoritative and practical, Cytochrome P450: In Vitro Methods and Protocols serves as a key guide for researchers in the area of discovery and development of new medicines.

Може също да ви хареса

Клиенти, които купиха тази книга, купиха също

Най-често търсени

Categories

Authors

Publishers

Продукти

Продукти

Най-често търсени

Categories

Authors

Publishers

Продукти

Продукти

Cytochrome P450

In Vitro Methods and Protocols

Информация за книгата

Пълно описание

Може също да ви хареса

Клиенти, които купиха тази книга, купиха също