Deformable Microparticles with Multiple Functions for Drug Delivery

Name: Deformable Microparticles with Multiple Functions for Drug Delivery
Brand: VDM Verlag Dr. Mueller E.K.
SKU: 9783639074956
Price: 59.66 EUR
Availability: InStock

Автор: Taili Thula

Език:

Корици: С меки корици

Издател: VDM Verlag Dr. Mueller E.K.

Наличност: Външен склад

Изпращаме след 14-21 дни

59.66 € 116.69 лв

Since the HIV epidemic of the 1990s, researchershave attempted to develop a red blood cell analog.Ev...

Информация за книгата

Автор

Taili Thula

Език

Английски език

Корици

Книга - С меки корици

Издадена

2008

страници

132

EAN

9783639074956

ISBN

3639074955

Enbook ID

06816750

Издател

VDM Verlag Dr. Mueller E.K.

Теглоt

186

Размери

152 x 229 x 7

Пълно описание

Since the HIV epidemic of the 1990s, researchershave attempted to develop a red blood cell analog.Even though some of these substitutes are now inPhase III of clinical trials, their use is limitedby side effects and short half-life in the humanbody. As a result, there is still a need for aneffective erythrocyte analog with minimumimmunogenic and side effects, so that it can be usedfor multiple applications. Finding new approachesto develop more efficient blood substitutes will notonly bring valuable advances in the clinicalapproach, but also in the area of in vitro testingof medical devices.This work examined the feasibility of creating adeformable multi-functional, biodegradable,biocompatible particle for applications in drugdelivery and device testing. As a preliminaryevaluation, different types of microcapsules weresynthesized using natural and synthetic polymers,various cross-linking agents, and diversemanufacturing techniques. After fullycharacterizing of each system, the most promisingred blood cell analog in terms of deformability,stability and toxicity was determined.

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Deformable Microparticles with Multiple Functions for Drug Delivery

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