Endotoxins: Structure, Function and Recognition

Name: Endotoxins: Structure, Function and Recognition
Brand: Springer
SKU: 9789048190775
Price: 209.92 EUR
Availability: InStock

Автор: Xiaoyuan Wang, Peter J. Quinn

Език:

Корици: С твърди корици

Издател: Springer

Наличност: Външен склад

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Endotoxins are potentially toxic compounds produced by Gram-negative bacteria including some pathoge...

Информация за книгата

Автор

Xiaoyuan Wang, Peter J. Quinn

Език

Английски език

Корици

Книга - С твърди корици

Издадена

2010

страници

415

EAN

9789048190775

ISBN

9048190770

Enbook ID

01976746

Издател

Springer

Теглоt

896

Размери

155 x 235 x 31

Пълно описание

Endotoxins are potentially toxic compounds produced by Gram-negative bacteria including some pathogens. Unlike exotoxins, which are secreted in soluble form by live bacteria, endotoxins are comprised of structural components of bacteria. §Endotoxins can cause a whole-body inflammatory state, sepsis, leading to low blood pressure, multiple organ dysfunction syndrome and death.§This book brings together contributions from researchers in the forefront of these subjects. It is divided into two sections: the first dealing with how endotoxins are synthesized and end up on the bacterial surface. The second discussed how endotoxins activate the Toll-like receptor TLR4 and, in turn, how TLR4 generates the molecular signals leading to infectious and inflammatory diseases.§The way endotoxins interact with the host cells is fundamental to understanding the mechanism of sepsis, and recent research on these aspects of endotoxins has served to illuminate previously undescribed functions of the innate immune system. This volume presents a description of endotoxins according to their genetic constitution, structure, function and mode of interaction with host cells.

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Endotoxins: Structure, Function and Recognition

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