Filaggrin

Name: Filaggrin
Brand: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
SKU: 9783662511176
Price: 93.01 EUR
Availability: InStock

Basic Science, Epidemiology, Clinical Aspects and Management

Автор: Jacob P. Thyssen, Howard I. Maibach

Език:

Корици: С меки корици

Издател: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG

Наличност: Външен склад

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93.01 € 181.90 лв

Filaggrin gene mutations are common in Europeans and their descendants, as well as in Asians, reachi...

Информация за книгата

Автор

Jacob P. Thyssen, Howard I. Maibach

Език

Английски език

Корици

Книга - С меки корици

Издадена

2016

страници

373

EAN

9783662511176

ISBN

3662511177

Enbook ID

13788448

Издател

Springer-Verlag Berlin and Heidelberg GmbH & Co. KG

Теглоt

8222

Размери

178 x 254 x 20

Пълно описание

Filaggrin gene mutations are common in Europeans and their descendants, as well as in Asians, reaching a prevalence of up to 10%. Filaggrin proteins are crucial for skin homeostasis as their metabolites maintain skin hydration, keep the skin pH low, and provide protection against solar radiation. FLG mutation carriers suffer from dry and scaly skin and have an increased transfer of allergens and chemicals across the epidermis. Moreover, they have 10% higher serum vitamin D levels, potentially affecting the propensity to develop other diseases. FLG loss-of-function mutations represent the strongest risk factor hitherto discovered for atopic dermatitis and are major predisposing factors for related asthma and hay fever. This textbook provides comprehensive and detailed coverage of the effects of FLG mutations in health and disease (cutaneous and non-cutaneous) and also discusses the basic science, epidemiology, management, and future research areas.

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Filaggrin

Basic Science, Epidemiology, Clinical Aspects and Management

Информация за книгата

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