Книга Fluorouracil Alberto C Dario Longinho

Fluorouracil

Synthesis, Health Effects & Role in Chemotherapy

Език: Английски език
Корици: С твърди корици
Издател: Nova Science Publishers Inc
Наличност: 50% вероятност
Ще претърсим света
182.12 356.20 лв
The fluoropyrimidine 5-fluorouracil (5-FU), an antimetabolite drug, works by being incorporated in t...

Информация за книгата

Език
Английски език
Корици
Книга - С твърди корици
Издадена
2012
страници
148
EAN
9781620819708
ISBN
9781620819708
Enbook ID
06430122
Теглоt
360
Размери
159 x 233 x 13

Пълно описание

The fluoropyrimidine 5-fluorouracil (5-FU), an antimetabolite drug, works by being incorporated in the RNA and DNA and by the inhibition of the nucleotide synthetic enzyme thymidylate synthase. It is widely used in the treatment of a range of cancers, including gastrointestinal, head and neck, and breast cancers. In this book, the authors present current research in the study of the synthesis, health effects and role in chemotherapy of fluorouracil. Topics discussed include the antiproliferative activities, cell-cycle regulation, apoptosis and cellular differentiation of acyclic 5-fluorouracil O, N-Acetals; 5-fluorouracil and its immunotoxicity and side effects; 5-fluorouracil application in the management of bleb failure; and cisplatin and 5-fluorouracil for the treatment of ovarian adenocarcinoma.

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