Gemcitabine

Name: Gemcitabine
Brand: Nova Science Publishers Inc
SKU: 9781633210110
Price: 149.15 EUR
Availability: InStock

Pharmacology, Clinical Uses & Potential Side Effects

Автор: Howard L Reese

Език:

Корици: С меки корици

Издател: Nova Science Publishers Inc

Наличност: 50% вероятност

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149.15 € 291.71 лв

Gemcitabine was synthesised in the 1980s at Lilly Research Laboratories (Eli Lilly and Co., Indianap...

Информация за книгата

Автор

Howard L Reese

Език

Английски език

Корици

Книга - С меки корици

Издадена

2014

страници

EAN

9781633210110

ISBN

9781633210110

Enbook ID

06430807

Издател

Nova Science Publishers Inc

Теглоt

198

Размери

144 x 224 x 8

Пълно описание

Gemcitabine was synthesised in the 1980s at Lilly Research Laboratories (Eli Lilly and Co., Indianapolis, IN). It was initially developed as an antiviral agent, but it had an extremely narrow therapeutic index due to its cytotoxicity against the parental cell lines. As it presented wide activity against various solid tumors it was then evaluated as an anticancer drug. This pyrimidine antimetabolite was firstly approved in 1996 by the Food and Drug Administration (FDA) for the treatment of pancreatic cancer. It is currently used for the treatment of many other malignancies such as lung cancer, breast cancer, lymphoma, bladder cancer, mesothelioma and ovarian cancer. This book discusses the molecular pharmacology, and the pharmacogenetics of gemcitabine. It also discusses the antineoplastic mechanism of gemcitabine on tumour cells; the systemic adverse effects; and provides detail on the clinical uses gemcitabine has on breast cancer.

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Gemcitabine

Pharmacology, Clinical Uses & Potential Side Effects

Информация за книгата

Пълно описание

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