Книга Gene Essentiality Long Jason Lu

Gene Essentiality

Methods and Protocols

Автор: Long Jason Lu
Език: Английски език
Корици: С твърди корици
Издател: Humana Press Inc.
Наличност: Външен склад в ограничено количество
Изпращаме след 11-15 дни
116.25 227.37 лв
This volume opens by covering two main types of approaches widely used to determine essential genes:...

Информация за книгата

Автор
Език
Английски език
Корици
Книга - С твърди корици
Издадена
2015
страници
248
EAN
9781493923977
ISBN
1493923978
Enbook ID
09104752
Издател
Теглоt
6952
Размери
178 x 254 x 262

Пълно описание

This volume opens by covering two main types of approaches widely used to determine essential genes: single-gene knockouts and transposon mutagenesis, in both prokaryotes and Candida albicans . Given the significant advancement in the computational predictions of microbial essential genes, the second half of the book examines four main types of approaches: comparative genomics, supervised machine learning, constraint-based methods, and corrections of transposon mutagenesis data, as well as databases and servers that are often used in studying gene essentiality. Written in the highly successful Methods in Molecular Biology series format, chapters include an introduction to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.§§Authoritative and up-to-date, Gene Essentiality: Methods and Protocols will aid researchers who wish to further our knowledge in this vital field of study.§

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