Genetic algorithm for haplotyping and block partitioning

Name: Genetic algorithm for haplotyping and block partitioning
Brand: VDM Verlag
SKU: 9783639237849
Price: 61.2 EUR
Availability: InStock

Автор: Nadezhda Sazonova

Език:

Корици: С меки корици

Издател: VDM Verlag

Наличност: Налично при издателя, по поръчка

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61.20 € 119.70 лв

A new algorithm for performing simultaneous haplotype resolution and block partitioning is proposed....

Информация за книгата

Автор

Nadezhda Sazonova

Език

Английски език

Корици

Книга - С меки корици

Издадена

2010

страници

132

EAN

9783639237849

ISBN

3639237846

Enbook ID

06831469

Издател

VDM Verlag

Теглоt

204

Размери

152 x 229 x 8

Пълно описание

A new algorithm for performing simultaneous haplotype resolution and block partitioning is proposed. The algorithm is based on genetic algorithm approach and the parsimonious principle. The multiloculs LD measure (Normalized Entropy Difference) is used as a block identification criterion. The proposed algorithm incorporates missing data is a part of the model and allows blocks of arbitrary length. In addition, the algorithm provides scores for the block boundaries which represent measures of strength of the boundaries at specific positions. The results show that the proposed genetic algorithm provides the accuracy of haplotype decomposition within the range of the same indicators shown by the other algorithms. The proposed algorithm is also used in a new population clustering algorithm, which extracts from the given genotype sample two clusters with substantially different block structures and finds haplotype resolution and block partitioning for each cluster.

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Genetic algorithm for haplotyping and block partitioning

Информация за книгата

Пълно описание

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