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Книга GPCRs Beata Jastrzebska

GPCRs

Structure, Function, and Drug Discovery

Автор: Beata Jastrzebska, Paul S. H. Park
Език: Английски език
Корици: С меки корици
Издател: Elsevier Books
Наличност: Налично при издателя, по поръчка
Изпращаме след 28-34 дни
191.91 € 375.34 лв
GPCRS: Structure, Function, and Drug Discovery provides a comprehensive overview of recent discoveri...

Информация за книгата

Автор
Beata Jastrzebska, Paul S. H. Park
Език
Английски език
Корици
Книга - С меки корици
Издадена
2019
страници
500
EAN
9780128162286
ISBN
0128162287
Enbook ID
22120894
Издател
Elsevier Books
Теглоt
1310
Размери
216 x 276 x 27

Пълно описание

GPCRS: Structure, Function, and Drug Discovery provides a comprehensive overview of recent discoveries and our current understanding of GPCR structure, signaling, physiology, pharmacology and methods of study. In addition to the fundamental aspects of GPCR function and dynamics, international experts discuss crystal structures, GPCR complexes with partner proteins, GPCR allosteric modulation, biased signaling through protein partners, deorphanization of GPCRs, and novel GPCR-targeting ligands that could lead to the development of new therapeutics against human diseases. GPCR association with, and possible therapeutic pathways for, retinal degenerative diseases, Alzheimer’s disease, Parkinson’s disease, cancer and diabetic nephropathy, among other illnesses, are examined in-depth. Addresses our current understanding and novel advances in the GPCR field, directing readers towards recent finding of key significance for translational medicineCombines a thorough discussion of structure and function of GPCRs with disease association and drug discoveryFeatures chapter contributions from international experts in GPCR structure, signaling, physiology and pharmacology

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