Hepatitis C Virus Treatment

Highly Effective Therapy with Direct Acting Antivirals and Associated Viral Resistance

Автор: Kazuaki Chayama

Език:

Корици: С меки корици

Издател: Springer Verlag, Singapore

Наличност: Външен склад

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This book introduces readers to Direct Acting Antiviral (DAAs) agents, newly developed drugs to trea...

Информация за книгата

Автор

Kazuaki Chayama

Език

Английски език

Корици

Книга - С меки корици

Издадена

2018

страници

EAN

9789811096105

Enbook ID

20125309

Издател

Springer Verlag, Singapore

Теглоt

194

Размери

155 x 235 x 5

Пълно описание

This book introduces readers to Direct Acting Antiviral (DAAs) agents, newly developed drugs to treat chronic hepatitis C virus infection, which have an excellent anti-viral effect on virus replication. These drugs have been developed to enhance the effect of interferon and ribavirin, as the resistant strains against each drug have been described both in vitro and in vivo and the existences of naturally occurring variants have been reported. However, since the combination of different classes of DAAs is sufficient to completely eradicate the virus without the need for interferon or ribavirin, the current treatment regimen does not include interferon. Ribavirin is used in combination with sofosbuvir, a potent polymerase inhibitor, to enhance its antiviral effects. Hepatitis C Virus Treatment offers readers a comprehensive guide to hepatitis C; describing the resistance profiles against these drugs and shedding light on the difficulties involved in DAA therapy and the direction of future treatments, it will equip doctors to understand the essentials of treating the disease. It also describes in detail new and innovative DAA treatments, the effects of the agents, and the characteristics of resistance, providing cutting-edge information not only for hepatologists, but also for researchers, clinical residents, and medical students.

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Highly Effective Therapy with Direct Acting Antivirals and Associated Viral Resistance

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