Книга Histone Methyltransferases Raphaël Margueron

Histone Methyltransferases

Methods and Protocols

Език: Английски език
Корици: С меки корици
Издател: Springer, Berlin
Наличност: Външен склад
Изпращаме след 10-18 дни
149.32 292.04 лв
This volume provides methods used to investigate histone methyltransferase function. Chapters guide...

Информация за книгата

Език
Английски език
Корици
Книга - С меки корици
Издадена
2023
страници
495
EAN
9781071624838
Enbook ID
43475477
Издател
Теглоt
883
Размери
178 x 254

Пълно описание

This volume provides methods used to investigate histone methyltransferase function. Chapters guide readers through a comprehensive set of approaches that detail phylogenetic diversity, histone demethylase activities in vitro, generating chromatin substrates, auto-methylation, quantification of metabolites, protein purification, crystallization, X-ray structure, cryogenic electron microscopy, assessing genome-wide patterns, CUT&Tag in mouse embryonic tissues, chemical biology approaches, peptide SPOT arrays, nascent chromatin capture, ectopic protein tethering, computational models, and development of methyltransferase inhibitors. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, Histone Methyltransferases: Methods and Protocols aims to be a useful and practical guide to new researchers and experts looking to expand their knowledge.

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