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Книга Histone Recognition Ming-Ming Zhou

Histone Recognition

Автор: Ming-Ming Zhou
Език: Английски език
Корици: С меки корици
Издател: Springer International Publishing AG
Наличност: Външен склад
Изпращаме след 5-8 дни
105.43 € 206.21 лв
This book provides a timely review of the role of histone modifications in epigenetic control of gen...

Информация за книгата

Автор
Ming-Ming Zhou
Език
Английски език
Корици
Книга - С меки корици
Издадена
2016
страници
282
EAN
9783319376660
ISBN
3319376667
Enbook ID
15194239
Издател
Springer International Publishing AG
Теглоt
4453
Размери
155 x 235 x 16

Пълно описание

This book provides a timely review of the role of histone modifications in epigenetic control of gene expression. Topics covered include: basic mechanisms of molecular recognition of histone post-translational modification (PTMs); combinatorial readout of histone PTMs by tandem epigenome reader domains; genome-wide profiling of histone PTM interactions; small molecule modulation of histone PTM interactions and their potential as a new approach to therapeutic intervention in human diseases. All chapters were written by leading scientists who made the original key discoveries of the structure and mechanism of evolutionarily conserved reader domains, which serve to direct gene transcription in chromatin through interactions with DNA-packing histones in a PTM-sensitive manner.

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