Innovative drug development for headache disorders

Автор: Jess Olsen, Nabih Ramadan

Език:

Корици: С твърди корици

Издател: Oxford University Press

Наличност: Външен склад

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228.05 € 446.03 лв

Migraine treatment improved considerably with the advent of the 'triptans' in the 1990s. While the d...

Информация за книгата

Автор

Jess Olsen, Nabih Ramadan

Език

Английски език

Корици

Книга - С твърди корици

Издадена

2008

страници

230

EAN

9780199552764

ISBN

0199552762

Enbook ID

04532886

Издател

Oxford University Press

Теглоt

569

Размери

177 x 254 x 18

Пълно описание

Migraine treatment improved considerably with the advent of the 'triptans' in the 1990s. While the drugs used previously for headache treatment had efficacy, some compounds had bothersome side effects and their overuse could lead to severe complications. In the early days of the triptans, it was widely presumed that migraine was no longer a treatment problem. However, it has gradually been recognized that a significant proportion of patients are not responsive to triptans or do not tolerate them. It is now clear that, even with effective treatment, patients with frequent migraine attacks are not treated well exclusively with acute medications. This is partly because patients are still bothered by the attacks and partly because frequent intake of acute medication may result in medication-overuse headache. These problems have led to a renewed interest in preventive migraine drugs.Part of the Frontiers in Headache Research series, this book summarizes the several promising new avenues for the development of future drugs for the treatment of migraine, including cortical-spreading depression inhibition, nitric oxide synthase inhibition and calcitonin gene-related peptide (CGRP) receptor antagonism, as well as other potential targets. The book presents frontline knowledge of these evolving modalities as far as it is available in the public domain. It is hoped that readers and their patients will find it exciting to learn about all the novel possibilities, and also that the impressive research advances in migraine will lead to increased funding, not only of migraine but also of other types of headache.

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Innovative drug development for headache disorders

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