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Книга Kainic Acid Elisabeth Leone

Kainic Acid

Автор: Elisabeth Leone
Език: Английски език
Корици: С твърди корици
Издател: Nova Science Publishers Inc
Наличност: 50% вероятност
Ще претърсим света
205.54 € 402.00 лв
Kainic acid is a naturally occurring amino acid that is isolated from red algae and is known to caus...

Информация за книгата

Автор
Elisabeth Leone
Език
Английски език
Корици
Книга - С твърди корици
Издадена
2014
страници
139
EAN
9781631179129
ISBN
9781631179129
Enbook ID
06433141
Издател
Nova Science Publishers Inc
Теглоt
390
Размери
157 x 229 x 16

Пълно описание

Kainic acid is a naturally occurring amino acid that is isolated from red algae and is known to cause amnesic shellfish poisoning via the activation of AMPA and kainate receptors in the hippocampus. Kainic acid is an analogue of glutamate and can modulate the transmission of glutamate. It''s neurotoxic potency has been shown to be 30 fold that of glutamate. Glutamate is an excitatory neurotransmitter that exerts its postsynaptic effects through ionotropic and metabotropic receptors. Of the ionotropic glutamate receptors (GluRs), kainic acid has a high affinity for 5 subtypes (KA1 and KA2, GluR5, GluR6, GluR7). Kainate receptors play a significant role in the physiological functioning and activity of numerous systems in the brain. This book discusses the neurotoxic properties of kainic acid, as well as the biological sources and clinical applications.

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