Matrix Metalloproteases

Methods and Protocols

Автор: Charles A. Galea

Език:

Корици: С твърди корици

Издател: Humana Press Inc.

Наличност: Външен склад

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164.48 € 321.69 лв

Since the identification of the first matrix metalloprotease (interstitial collagenase or MMP-1) mor...

Информация за книгата

Автор

Charles A. Galea

Език

Английски език

Корици

Книга - С твърди корици

Издадена

2017

страници

314

EAN

9781493968619

ISBN

1493968610

Enbook ID

15447500

Издател

Humana Press Inc.

Теглоt

7611

Размери

178 x 254 x 24

Пълно описание

Since the identification of the first matrix metalloprotease (interstitial collagenase or MMP-1) more than 20 closely related and evolutionarily conserved vertebrate MMPs have been discovered. Chapters in this volume detail methods and protocols on recent advances in the expression and purification of MMPs, biophysical methods such as X-ray crystallography, NMR spectroscopy and small angle X-ray scattering, computational and experimental methods for determining MMP specificity, methods for detecting MMP activity in vitro and in vivo , and methods for the development and characterization of MMP-based inhibitors as potential therapeutics for the treatment of various diseases. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Matrix Metalloproteases: Methods and Protocols aims to ensure successful results in the further study of this vital field.

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Matrix Metalloproteases

Methods and Protocols

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