Книга Hepatitis B and D Protocols Robert K. Hamatake

Hepatitis B and D Protocols

Volume 1: Detection, Genotypes, and Characterization

Език: Английски език
Корици: С твърди корици
Издател: Humana Press Inc.
Наличност: Външен склад
Изпращаме след 10-13 дни
154.19 301.56 лв
Despite the availability of an effective vaccine, there are still 400 million people, worldwide who...

Информация за книгата

Език
Английски език
Корици
Книга - С твърди корици
Издадена
2004
страници
376
EAN
9781588291059
ISBN
1588291057
Enbook ID
03615937
Издател
Теглоt
729
Размери
152 x 229 x 25

Пълно описание

Despite the availability of an effective vaccine, there are still 400 million people, worldwide who are chronically infected with hepatitis B virus (HBV). For them, the vaccine, as currently applied, has no value. Given the possible consequences of HBV infection, the number of those chronically infected with HBV presents an enormous public health challenge. For example, the major etiology of hepatocellular carcinoma (HCC) is chronic infection with HBV. Although fifth in cancer incidence, worldwide, HCC/liver cancer is the third leading cause of cancer death. The high mortality as- ciated with HCC arises because the disease is often detected late and is unresponsive to treatment. The number of deaths caused by PHCC is expected to rise over the next 20 years. Those chronically infected with HBV have a life risk of death to HCC of between 10 and 25%. Even the limited efficacy of drugs for the treatment of chronic HBV helps underscore the point that this disease is responsive to therapy. Drugs that target the polymerase (e. g. , hepsera and lamivudine) and interferon alpha represent two distinct strategies and show that both conventional antiviral and immunothe- peutic approaches can be used in management. However, the current inventory of therapeutics is inadequate. Interferon alpha is of limited value, only parenterally ava- able, and fraught with adverse reactions.

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