Microstructured Interpenetrating Polymer Network Drug Delivery System

Name: Microstructured Interpenetrating Polymer Network Drug Delivery System
Brand: LAP Lambert Academic Publishing
SKU: 9783846524398
Price: 53.86 EUR
Availability: InStock

Development of Novel Interpenetrating Polymer Network Hydrogel Microspheres For Controlled Release of Diclofenac Sodium

Автор: Subham Banerjee, Somasree Ray, Pronobesh Chattopadhyay

Език:

Корици: С меки корици

Издател: LAP Lambert Academic Publishing

Наличност: Външен склад

Изпращаме след 5-8 дни

53.86 € 105.33 лв

Novel interpenetrating network (IPN) hydrogel microspheres, consisting of xanthan gum and poly(vinyl...

Информация за книгата

Автор

Subham Banerjee, Somasree Ray, Pronobesh Chattopadhyay

Език

Английски език

Корици

Книга - С меки корици

Издадена

2011

страници

128

EAN

9783846524398

Enbook ID

06883953

Издател

LAP Lambert Academic Publishing

Теглоt

209

Размери

150 x 220 x 8

Пълно описание

Novel interpenetrating network (IPN) hydrogel microspheres, consisting of xanthan gum and poly(vinyl alcohol) were prepared by water-in-oil emulsion crosslinking method using glutaraldehyde for the controlled release of diclofenac sodium,as a model drug.Various formulations were prepared by changing the ratio of XG:PVA, extent of cross-linking in order to optimize the formulation variables on drug encapsulation efciency, and release rate. Formation of IPN and the chemical stability of DS after preparation of microspheres was confrmed by FTIR, DSC & XRD analysis were done which confrmed molecular dispersion of DS in the IPN. Microspheres formed were spherical with smooth surfaces, as evidenced by SEM & mean particle size measured by laser light scattering technique. Drug encapsulation of up to 82.94% was achieved by UV method. Both equilibrium & dynamic swelling studies and in vitro release studies were performed in pH 1.2 and 7.4. Release data indicated Fickian trend of drug release. In vivo pharmacokinetic data showed prolonged drug release as compared with DS solution. Based on the results it was concluded that these IPN microspheres provided controlled release application of DS

Може също да ви хареса

Клиенти, които купиха тази книга, купиха също

Най-често търсени

Categories

Authors

Publishers

Продукти

Продукти

Най-често търсени

Categories

Authors

Publishers

Продукти

Продукти

Microstructured Interpenetrating Polymer Network Drug Delivery System

Development of Novel Interpenetrating Polymer Network Hydrogel Microspheres For Controlled Release of Diclofenac Sodium

Информация за книгата

Пълно описание

Може също да ви хареса

Клиенти, които купиха тази книга, купиха също