Neuropilin

Name: Neuropilin
Brand: Springer-Verlag New York Inc.
SKU: 9781461349327
Price: 157.41 EUR
Availability: InStock

From Nervous System to Vascular and Tumor Biology

Автор: Dominique Bagnard

Език:

Корици: С меки корици

Издател: Springer-Verlag New York Inc.

Наличност: Външен склад

Изпращаме след 5-8 дни

157.41 € 307.86 лв

Cell adhesion is one of the most important properties controlling embryonic development. Extremely p...

Информация за книгата

Автор

Dominique Bagnard

Език

Английски език

Корици

Книга - С меки корици

Издадена

2012

страници

142

EAN

9781461349327

ISBN

9781461349327

Enbook ID

06617922

Издател

Springer-Verlag New York Inc.

Теглоt

272

Размери

155 x 235 x 10

Пълно описание

Cell adhesion is one of the most important properties controlling embryonic development. Extremely precise cell-cell contacts are established according to the nature of adhesion molecules that are expressed on the cell surface. The identifica tion of several families of adhesion molecules, well conserved throughout evolu tion, has been the basis of a considerable amount of work over the past 20 years that contributed to establish functions of cell adhesion in almost all organs. Nowadays, cell adhesion molecules are not just considered as cellular glue but are thought to play critical roles in cell signaling. Their ability to influence cell proliferation, mi gration, or differentiation depends on both cell surface adhesion properties and acti vation of intracellular pathways. The next challenge will be to understand how these molecules interact with each other to ensure specific functions in the morphogen esis of very sophisticated systems. Indeed, by exploring the cellular and molecular mechanisms of nervous system development, the group of H. Fujisawa in Japan identified in 1987 an adhesion molecule, neuropilin, highly expressed in the neuro pile of amphibian optic tectum. Ten years later, two groups discovered that neuropilin is a receptor for guidance signals of the semaphorin family. Axon guidance is a critical step during brain development and the mechanisms ensuring growth cone navigation are beginning to be well understood. The semaphorins are bifunctional signals defining permissive or inhibitory pathways sensed by the growth cone.

Може също да ви хареса

Клиенти, които купиха тази книга, купиха също

Най-често търсени

Categories

Authors

Publishers

Продукти

Продукти

Най-често търсени

Categories

Authors

Publishers

Продукти

Продукти

Neuropilin

From Nervous System to Vascular and Tumor Biology

Информация за книгата

Пълно описание

Може също да ви хареса

Клиенти, които купиха тази книга, купиха също