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Oncogenes Meet Metabolism

Name: Oncogenes Meet Metabolism
Brand: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
SKU: 9783540794776
Price: 157.76 EUR
Availability: InStock

From Deregulated Genes to a Broader Understanding of Tumour Physiology

Автор: G. Kroemer, D. Mumberg, H. Keun, B. Riefke

Език:

Корици: С твърди корици

Издател: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG

Наличност: Външен склад

Изпращаме след 10-13 дни

157.76 € 308.56 лв

In 1920s, Otto Warburg described the phenomenon of aerobic glycolysis , the ability of tumour cells...

Информация за книгата

Автор

G. Kroemer, D. Mumberg, H. Keun, B. Riefke

Език

Английски език

Корици

Книга - С твърди корици

Издадена

2008

страници

265

EAN

9783540794776

ISBN

3540794778

Enbook ID

01570245

Издател

Springer-Verlag Berlin and Heidelberg GmbH & Co. KG

Теглоt

490

Размери

155 x 235 x 21

Пълно описание

In 1920s, Otto Warburg described the phenomenon of aerobic glycolysis , the ability of tumour cells to convert glucose to lactate in the presence of normal oxygen conditions. Warburg s hypothesis of an altered metabolism in cancer cells found no immediate acceptance, though it was latter confirmed for most human tumours. With the advent of molecular biology the focus in tumour research has shifted towards the search for oncogenes. However, the interest in cancer molecular profiling eventually led to a renaissance of the Warburg effect trying to combine genetic alterations with effects on metabolism with the help of modern analytic technologies to rapidly analyze broad varieties of metabolites in various tissues and bodyfluids (metabonomics).