Proteases in Physiology and Pathology

Автор: Sajal Chakraborti, Naranjan S. Dhalla

Език:

Корици: С твърди корици

Издател: Springer Verlag, Singapore

Наличност: Външен склад

Изпращаме след 10-13 дни

157.89 € 308.81 лв

Using a multidisciplinary approach, this book describes the biochemical mechanisms associated with d...

Информация за книгата

Автор

Sajal Chakraborti, Naranjan S. Dhalla

Език

Английски език

Корици

Книга - С твърди корици

Издадена

2017

страници

619

EAN

9789811025129

ISBN

9811025126

Enbook ID

13805147

Издател

Springer Verlag, Singapore

Теглоt

1225

Размери

155 x 235 x 32

Пълно описание

Using a multidisciplinary approach, this book describes the biochemical mechanisms associated with dysregulation of proteases and the resulting pathophysiological consequences. It highlights the role and regulation of different types of proteases as well as their synthetic and endogenous inhibitors. The role of proteases was initially thought to be limited to general metabolic digestion. However, we now know that the role of protein breakdown is much more complex, and proteases have multiple functions: they are coupled to turnover and can affect protein composition, function and synthesis. In addition to eliminating abnormal proteins, breakdown has many modulatory functions, including activating and inactivating enzymes, modulating membrane function, altering receptor channel properties, affecting transcription and cell cycles and forming active peptides. The ubiquity of proteases in nature makes them an important target for drug development. This in-depth, comprehensive is a valuable resource for researchers involved in identifying new targets for drug development. With its multidisciplinary scope, it bridges the gap between fundamental and translational research in the biomedical and pharmaceutical industries, making it thought-provoking reading for scientists in the field.

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Proteases in Physiology and Pathology

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