Protein'Protein Interactions

Name: Protein'Protein Interactions
Brand: Humana Press Inc.
SKU: 9781617373732
Price: 173.99 EUR
Availability: InStock

Methods and Applications

Автор: Haian Fu

Език:

Корици: С меки корици

Издател: Humana Press Inc.

Наличност: Налично при издателя, по поръчка

Изпращаме след 17-27 дни

173.99 € 340.29 лв

As the mysteries stored in our DNA have been more completely revealed, scientists have begun to face...

Информация за книгата

Автор

Haian Fu

Език

Английски език

Корици

Книга - С меки корици

Издадена

2010

страници

532

EAN

9781617373732

ISBN

1617373737

Enbook ID

05259898

Издател

Humana Press Inc.

Теглоt

920

Размери

152 x 229 x 34

Пълно описание

As the mysteries stored in our DNA have been more completely revealed, scientists have begun to face the extraordinary challenge of unraveling the int- cate network of protein protein interactions established by that DNA fra- work. It is increasingly clear that proteins continuously interact with one another in a highly regulated fashion to determine cell fate, such as proliferation, diff- entiation, or death. These protein protein interactions enable and exert str- gent control over DNA replication, RNA transcription, protein translation, macromolecular assembly and degradation, and signal transduction; essentially all cellular functions involve protein protein interactions. Thus, protein p- tein interactions are fundamental for normal physiology in all organisms. Alt- ation of critical protein protein interactions is thought to be involved in the development of many diseases, such as neurodegenerative disorders, cancers, and infectious diseases. Therefore, examination of when and how protein p- tein interactions occur and how they are controlled is essential for understa- ing diverse biological processes as well as for elucidating the molecular basis of diseases and identifying potential targets for therapeutic interventions. Over the years, many innovative biochemical, biophysical, genetic, and computational approaches have been developed to detect and analyze p- tein protein interactions. This multitude of techniques is mandated by the diversity of physical and chemical properties of proteins and the sensitivity of protein protein interactions to cellular conditions.

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