Seeking Cures

Design of Therapies for Genetically Determined Diseases

Автор: Moyra Smith

Език:

Корици: С твърди корици

Издател: Oxford University Press Inc

Наличност: Външен склад

Изпращаме след 10-18 дни

94.89 € 185.59 лв

Progress in molecular and cellular biology has greatly enhanced our ability to accurately diagnose d...

Информация за книгата

Автор

Moyra Smith

Език

Английски език

Корици

Книга - С твърди корици

Издадена

2013

страници

320

EAN

9780199915866

ISBN

0199915865

Enbook ID

04536631

Издател

Oxford University Press Inc

Теглоt

588

Размери

155 x 244 x 20

Пълно описание

Progress in molecular and cellular biology has greatly enhanced our ability to accurately diagnose diseases that are caused by gene mutations, changes in genome structures, and altered gene expression; increased emphasis is now placed on translational research the clinical treatment of these genetically determined diseases. Seeking Cures outlines the progress and implications of science's quest to identify therapeutic targets and initiate novel treatments at the gene, RNA, protein, and physiological levels. Also considered are aspects of treatment at the cellular level (e.g., those with hematopoietic stem cells or induced pluripotent stem cells). Topics covered in this text include: * outline of the processes typical for identifying disease-modifying therapies * examples of newer therapeutic approaches in use or under investigation to treat lysosomal storage diseases, inborn errors of metabolism, mitochondrial functional defects, and specific monogenic diseases * therapeutic designs for specific complex common diseases, including Alzheimer's disease, cancer, and autism Through these specific examples, Seeking Cures provides a glimpse at the pursuit-and future-of personalized medicine.

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Seeking Cures

Design of Therapies for Genetically Determined Diseases

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