SH2 Domains

Methods and Protocols

Автор: Kazuya Machida, Bernard A. Liu

Език:

Корици: С твърди корици

Издател: Humana Press Inc.

Наличност: Външен склад в ограничено количество

Изпращаме след 11-15 дни

209.44 € 409.63 лв

This volume covers an array of techniques available for studying SH2 domains and phosphotyrosine sig...

Информация за книгата

Автор

Kazuya Machida, Bernard A. Liu

Език

Английски език

Корици

Книга - С твърди корици

Издадена

2017

страници

558

EAN

9781493967605

ISBN

1493967606

Enbook ID

14277282

Издател

Humana Press Inc.

Теглоt

1259

Размери

178 x 254 x 35

Пълно описание

This volume covers an array of techniques available for studying SH2 domains and phosphotyrosine signaling. The book is divided into six parts: Part I outlines the history of SH2, technology development, and cell signaling; Part II focuses on computational approaches and tools used for identification, classification, and predictions of SH2 domain binding partners; Part III details various ways to prepare the SH2 domains as experimental reagents; Part IV presents methods for structural analysis and conventional binding assays using SH2 domains; Part V describes high-throughput and proteomics approaches to aid in analyzing SH2-mediated interactions; and Part VI covers applications for SH2 domain to functional and imaging analyzes. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, SH2 Domains: Methods and Protocols is a valuable resource for computational biologists, biochemists, structural biologists, cell biologists, pathologists, and people interested in SH2 domains and phosphotyrosine signaling. Researchers who are investigating how protein interaction domain mediate specificity in signaling systems may also find this book informative.

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SH2 Domains

Methods and Protocols

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