Stem Cell Genetics for Biomedical Research

Past, Present, and Future

Автор: Raul Delgado-Morales

Език:

Корици: С твърди корици

Издател: Springer International Publishing AG

Наличност: Външен склад в ограничено количество

Изпращаме след 13-18 дни

167.89 € 328.36 лв

This book looks at where stem cell technology is presently and how it is instrumental in advancing t...

Информация за книгата

Автор

Raul Delgado-Morales

Език

Английски език

Корици

Книга - С твърди корици

Издадена

2018

страници

426

EAN

9783319906942

ISBN

3319906941

Enbook ID

19251153

Издател

Springer International Publishing AG

Теглоt

6514

Размери

155 x 235 x 29

Пълно описание

This book looks at where stem cell technology is presently and how it is instrumental in advancing the field of disease modeling and cell transplantation. By focusing on major human disorders such as Alzheimer's disease, cancer, and heart disorders, the book will summarize the major findings in the field of human stem cells and dissect the current limitations on our understanding of stem cells biology. The chapters will focus on the genetics, genomics, epigenetics and physiology of stem cells models, together with technological advances on molecular biology such as CRISPR/Cas9 or epigenetic editing, that will be instrumental in the future of human disease modeling and treatment. In base of the limitations of current disease models and in front of the unmet necessity of finding therapeutical interventions for human disorders, the availability of stem cell technology has opened new doors for several fields. The unlimited self-renewal capacity and more extensive differentiation potential of stem cells offers a theoretically inexhaustible and replenishable source of any cell subtype. Since Professor Shinya Yamanaka described it, 10 years ago in his seminal paper, that somatic cells could be reprogrammed to inducible stem cells (iPSC) just by expressing four transcription factors, the field of has exploded, especially its applications in biomedical research.

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