STRUCTURE-ACTIVITY RELATIONSHIPS FOR PHARMACOTOXICOLOGICAL ENDPOINTS

Name: STRUCTURE-ACTIVITY RELATIONSHIPS FOR PHARMACOTOXICOLOGICAL ENDPOINTS
Brand: LAP Lambert Academic Publishing
SKU: 9783838356808
Price: 72.24 EUR
Availability: InStock

DEVELOPMENT OF STRUCTURE-ACTIVITY RELATIONSHIPS FOR PHARMACOTOXICOLOGICAL ENDPOINTS RELEVANT TO EUROPEAN UNION LEGISLATION

Автор: Iglika Lessigiarska, Andrew P. Worth, Mark T.D. Cronin

Език:

Корици: С меки корици

Издател: LAP Lambert Academic Publishing

Наличност: Външен склад

Изпращаме след 5-8 дни

72.24 € 141.29 лв

Quantitative structure-activity relationships (QSARs) are computer-based mathematical models that gi...

Информация за книгата

Автор

Iglika Lessigiarska, Andrew P. Worth, Mark T.D. Cronin

Език

Английски език

Корици

Книга - С меки корици

Издадена

2010

страници

232

EAN

9783838356808

Enbook ID

06995262

Издател

LAP Lambert Academic Publishing

Теглоt

362

Размери

150 x 220 x 14

Пълно описание

Quantitative structure-activity relationships (QSARs) are computer-based mathematical models that give information on the potential biological effects of compounds on the basis of their chemical structure alone. In this book, a research project on the development of QSARs for a range of toxicological endpoints, including cytotoxicity and acute toxicity, and biokinetic parameters related to the penetration of chemical compounds across the blood-brain barrier, is presented. Increasingly, legislation on the assessment and management of chemical risks, such as the REACH (Registration, Evaluation and Authorisation of Chemicals) Regulation in European Union, foresee an expanded use of QSARs as an alternative approach to (animal) testing of toxicity for the regulatory assessment of chemicals and chemical products. The research presented was performed at the Institute for Health & Consumer Protection (IHCP) of the European Commission's Joint Research Centre (JRC) and at Liverpool John Moores University (LJMU) as a part of Iglika Lessigiarska's PhD project.

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STRUCTURE-ACTIVITY RELATIONSHIPS FOR PHARMACOTOXICOLOGICAL ENDPOINTS

DEVELOPMENT OF STRUCTURE-ACTIVITY RELATIONSHIPS FOR PHARMACOTOXICOLOGICAL ENDPOINTS RELEVANT TO EUROPEAN UNION LEGISLATION

Информация за книгата

Пълно описание

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