Target Discovery and Validation Reviews and Protocols

Name: Target Discovery and Validation Reviews and Protocols
Brand: Humana Press Inc.
SKU: 9781617376993
Price: 125.95 EUR
Availability: InStock

Emerging Strategies for Targets and Biomarker Discovery, Volume 1

Автор: Mouldy Sioud

Език:

Корици: С меки корици

Издател: Humana Press Inc.

Наличност: Външен склад в ограничено количество

Изпращаме след 13-18 дни

125.95 € 246.35 лв

Target discovery is a field that has existed for several years but is so vibrant today because of th...

Информация за книгата

Автор

Mouldy Sioud

Език

Английски език

Корици

Книга - С меки корици

Издадена

2010

страници

354

EAN

9781617376993

ISBN

161737699X

Enbook ID

02717300

Издател

Humana Press Inc.

Теглоt

541

Размери

152 x 229 x 27

Пълно описание

Target discovery is a field that has existed for several years but is so vibrant today because of the recent progress in our understanding of the molecular mechanisms of many human diseases and the technical advances in target identification and validation. More sophisticated gene profiling technologies, such as DNA microarrays and serial analysis of gene expression, permit rapid identification of lead targets. Moreover, analysis of gene networks in living organisms allows the identification of target genes that operate in defined physiological pathways. With the sequencing of several genomes completed and the rapidly growing gene expression databases, there is now greater impetus than ever before for in silico discovery of therapeutic targets. Also, recent advances in genetic technologies have increased our ability to generate mouse models for human diseases. The implications of these genetically modified animals in drug development are several, including identification of new drug targets, predicting efficacy, and uncovering possible side effects. Together, these recent technical advances should allow researchers to make the most informed choice early and advance the chosen targets toward clinical studies. Regarding cancers, any difference between a cancer and a normal cell could potentially be exploited as a therapeutic target. The hope is that drugs targeting specific constituents or pathways in cancer cells will provide more effective therapy, either alone or in combination with other currently used anticancer drugs. In addition to drug targets, identifying new target antigens remains as much of a challenge as improving tumor vaccines already in the clinic.

Може също да ви хареса

Клиенти, които купиха тази книга, купиха също

Най-често търсени

Categories

Authors

Publishers

Продукти

Продукти

Най-често търсени

Categories

Authors

Publishers

Продукти

Продукти

Target Discovery and Validation Reviews and Protocols

Emerging Strategies for Targets and Biomarker Discovery, Volume 1

Информация за книгата

Пълно описание

Може също да ви хареса

Клиенти, които купиха тази книга, купиха също