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Книга The CD38 molecule Ahlem Mokrane

The CD38 molecule

Автор: Ahlem Mokrane
Език: Английски език
Корици: С меки корици
Издател: LAP Lambert Academic Publishing
Наличност: Външен склад
Изпращаме след 8-11 дни
26.66 € 52.15 лв
CD38 is a transmembrane glycoprotein type II, which is expressed on normal hematopoietic cells and i...

Информация за книгата

Автор
Ahlem Mokrane
Език
Английски език
Корици
Книга - С меки корици
Издадена
2018
страници
84
EAN
9786138339779
Enbook ID
19185748
Издател
LAP Lambert Academic Publishing
Теглоt
143
Размери
150 x 220 x 5

Пълно описание

CD38 is a transmembrane glycoprotein type II, which is expressed on normal hematopoietic cells and in non-hematopoietic tissues. Notably, CD38 is highly expressed in multiple myeloma, chronic lymphocytic leukemia, and other diseases. CD38 plays several roles, including ectoenzyme, receptor, adhesion molecule, and is involved in signal transduction. The cytotoxic mechanisms of daratumumab, which is considered a new high affinity human therapeutic mAb against a single CD38 epitope. CD38 represents a promising target for mAb-based immunotherapy, which has already and will continue to transform the treatment landscape into diseases, including multiple myeloma.

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