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Updates on Clostridioides difficile in Europe

Name: Updates on Clostridioides difficile in Europe
Brand: Springer, Berlin
SKU: 9783031421075
Price: 168.24 EUR
Availability: InStock

Advances in Microbiology, Infectious Diseases and Public Health Volume 18

Автор: Paola Mastrantonio, Maja Rupnik

Език:

Корици: С твърди корици

Издател: Springer, Berlin

Наличност: Външен склад

Изпращаме след 10-13 дни

168.24 € 329.06 лв

This fully updated second edition outlines the currently available clinical, epidemiological and exp...

Информация за книгата

Автор

Paola Mastrantonio, Maja Rupnik

Език

Английски език

Корици

Книга - С твърди корици

Издадена

2023

страници

372

EAN

9783031421075

Enbook ID

43829994

Издател

Springer, Berlin

Теглоt

896

Размери

178 x 254

Пълно описание

This fully updated second edition outlines the currently available clinical, epidemiological and experimental data on Clostridioides difficile infections(CDI) with special emphasis on studies and results achieved in Europe. The incidence and severity of CDI has increased significantly over the last decade, and the book explains why C. difficile, recently reclassified as Clostridioides difficile, remains a significant challenge, also from economic perspective, to health care systems all over the world. The different reservoirs of this ubiquitous microorganism are reviewed as well as the different factors contributing to its virulence, such as toxins and biofilm formation. The rapid evolution of antibiotic resistance is clearly a concern and in a specific way can influence the CDI epidemiology. Additionally, new emerging strains and comparative genomics studies are taken into consideration for their relevance from epidemiological and evolutionary point of view. The book also gives an overview on diagnostics, therapy and surveillance, all of which are still challenging. Therefore, a closer look is taken on the effect of probiotics as an alternative to antibiotics, for prevention and treatment of CDI. Fecal transplantation from healthy donors, passive immunotherapies and vaccines for patients with recurrences are also discussed in dedicated chapters. New topics included sporulation and membrane vesicles in C. difficile. The book closes with a summary of the history and the achievements of the European Society of Clinical Microbiology and Infectious Diseases Study Group for Clostridium difficile (ESGCD) written by the current and past presidents of the Society. It is the aim of this book to raise awareness on CDI and to disseminate updated information on its prevention, diagnosis and treatment.