Vascular Endothelium

Name: Vascular Endothelium
Brand: Springer-Verlag New York Inc.
SKU: 9781468485349
Price: 59.09 EUR
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Receptors and Transduction Mechanisms

Автор: J. Catravas

Език:

Корици: С меки корици

Издател: Springer-Verlag New York Inc.

Наличност: Външен склад в ограничено количество

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Beyond their obvious role of a barrier between blood and tissue, vascular endothelial cells are now...

Информация за книгата

Автор

J. Catravas

Език

Английски език

Корици

Книга - С меки корици

Издадена

2013

страници

308

EAN

9781468485349

ISBN

1468485342

Enbook ID

02643752

Издател

Springer-Verlag New York Inc.

Теглоt

618

Размери

178 x 254 x 18

Пълно описание

Beyond their obvious role of a barrier between blood and tissue, vascular endothelial cells are now firmly established as active and essential participants in a host of crucial physiological and pathophysiological functions. Probably the two most important factors responsible for promoting the current knowledge of endothelial functions are 1) observations in the late sixties-early seventies that many non-ventilatory properties of the lung could be attributed to the pulmonary endothelium and 2) the establishment, in the early and mid-seventies of procedures for routine culture of vascular endothelial cells. Many of these endothelial functions require the presence of receptors on the surface of the plasma membrane. There is now evidence for the existence among others of muscarinic, a-and /3-adrenergic, purine, insulin, histamine, bradykinin, lipoprotein, thrombin, paf, fibronectin, vitronectin, interleukin and albumin receptors. For some of these ligands, there is evidence only for the existence of endothelial binding sites. Traditionally, agonist binding must elicit a response for the binding site to be considered a receptor and, in some cases, the nature of the response resulting from the interaction of a substance with the endothelium remains unclear. It is beyond the scope of this introduction to even enumerate the various endothelial homeostatic processes. This monograph contains the proceedings of the Advanced Studies Institute on "Vascular Endothelium: Receptors and Transduction Mechanisms" held in Porto Carras, Greece from June 18-29, 1988.

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Vascular Endothelium

Receptors and Transduction Mechanisms

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